1. Gastric acid resistance:
One of the keys to the design of Enteric-coated Hollow Capsules is their gastric acid resistance. The outer layer of the capsule is covered with a special material that can withstand the highly acidic environment of gastric acid. In the stomach, the pH of gastric acid is usually between 1.5 and 3, which can be a problem for many drugs because they are easily degraded or inactive in this acidic environment. The outer layer material of the Enteric-coated capsule usually prevents the capsule from dissolving in the stomach until it reaches the small intestine. This is because the pH of the small intestine is relatively neutral (about 6 to 7), which is more suitable for the absorption and utilization of many drugs.
2. Dissolution timing control:
Once the Enteric-coated Hollow Capsule reaches the small intestine, it is designed to promote rapid dissolution. The outer layer material of this capsule is more sensitive to the neutral pH environment of the small intestine, which allows the capsule to dissolve quickly, releasing the drug inside. This precise control of the dissolution timing is critical to the success of drug therapy because it ensures that the drug is released in the most favorable area and time period of the digestive tract.
3. Delayed drug release:
Enteric-coated Hollow Capsules also have the property of delayed drug release. This delayed release can be achieved in a variety of ways, such as the outer layer material of the capsule can be designed to delay dissolution under specific digestive conditions, or the structure of the capsule can control the release rate of the drug. This delayed release is very useful for treatments that require the release of drugs at a specific time point or in a specific location in the digestive tract, which can maximize the effectiveness and absorption of the drug.
4. Protecting drugs from being destroyed:
Another important function of Enteric-coated Hollow Capsules is to protect the internal drugs from being destroyed by gastric acid and digestive enzymes. The outer layer material of the capsule can act as a protective barrier to prevent the effects of gastric acid and gastric digestive enzymes on the drugs. This protective effect can ensure that the drug maintains its integrity and activity before reaching the small intestine, thereby improving the therapeutic effect and reducing the risk of adverse reactions.
5. Targeted delivery:
Enteric-coated Hollow Capsules can be designed to release drugs at specific locations or time periods in the digestive tract, which is called targeted delivery. For example, some drugs may need to be released in specific parts of the intestine to maximize absorption or to avoid possible discomfort caused by the stomach. By precisely controlling the location and timing of release, this targeted delivery can optimize the efficacy of the drug and help physicians tailor treatment to the specific needs of their patients.
Enteric-coated Hollow Capsules
Product application: It is often used in special packaging for drugs or health care products that are irritating to the stomach or are unstable in the presence of acid, and that need to be dissolved in the intestine and exert their curative effect.
Product function: Intestinal positioning administration, reducing adverse reactions. Targeted fixed-point release: no disintegration and no cracks in gastric juice for two hours, and drug release in intestinal juice within 30 minutes, providing a perfect solution for protein polypeptide drugs and live bacteria preparations.