1.Choose the appropriate size capsules: Determine the desired capsule size based on the dosage requirements and the quantity of the substance you want to encapsulate. Gelatin capsules come in various sizes, such as 00, 0, 1, 2, 3, and 4, with 00 being the largest and 4 being the smallest.
2.Prepare the filling material: Grind or powder the supplement or herbal remedy using a mortar and pestle, grinder, or suitable equipment. Ensure that the substance is finely ground to fit into the capsules.
3.Open the gelatin capsules: Carefully separate the two halves of the gelatin capsule by gently pulling them apart. Most capsules have a shorter half (the cap) and a longer half (the body).
4.Fill the capsules: Take one half of the gelatin capsule (the body) and hold it with the open end facing upward. Using a clean and dry capsule filling machine, capsule filler, or a suitable alternative, place the open end of the capsule onto the filling platform or tray. Pour the powdered substance into the capsule body, filling it as desired.
5.Tamp down the filling (optional): If needed, use a tamper or the back of a spoon to gently press down and compact the powdered substance in the capsule body. This helps ensure a consistent dosage and allows more material to fit into the capsule.
6.Seal the capsules: Take the other half of the gelatin capsule (the cap) and place it over the filled body. Press the two halves together until they firmly close and create a seal. Ensure that the capsules are properly sealed to prevent any leakage.
7.Repeat the process: Continue filling the remaining gelatin capsules until you have encapsulated the desired quantity of the supplement or herbal remedy.
8.Clean up: Remove any excess powder or spills from the filling equipment or work area. Clean the equipment thoroughly according to the manufacturer's instructions to maintain hygiene.
Enteric-coated Hollow Capsules
Product introduction: Enteric gelatin hollow capsules are made of gelatin and enteric coating materials.
Product Category: Pharmaceutical Excipients
Product application: It is often used in special packaging for drugs or health care products that are irritating to the stomach or are unstable in the presence of acid, and that need to be dissolved in the intestine and exert their curative effect.
Product function: Intestinal positioning administration, reducing adverse reactions. Targeted fixed-point release: no disintegration and no cracks in gastric juice for two hours, and drug release in intestinal juice within 30 minutes, providing a perfect solution for protein polypeptide drugs and live bacteria preparations.
Product advantages: Intestinal-targeted drug delivery can improve drug efficacy and reduce dosage, and at the same time, it can reduce adverse reactions and facilitate the use of patients; it can also avoid the degradation of oral protein polypeptide drugs or health care products, providing the best absorption site for drugs.