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中文简体There are different options for sealing or closure mechanisms for hard capsules. The choice of sealing method depends on factors such as the type of capsule, intended use, and manufacturing capabilities. Here are some common options:
1.Gelatin Capsules:
a. Pre-closed Capsules: These capsules come pre-sealed from the manufacturer and do not require any additional sealing steps during the filling process.
b. Banding: A small gelatin band is applied around the joint of the capsule halves to secure them together. This method provides a tamper-evident seal.
c. Heat Sealing: Heat can be applied to the joint of the capsule halves, causing the gelatin to melt and form a seal upon cooling.
2.HPMC (Hydroxypropyl Methylcellulose) or Vegetarian Capsules:
a. Pre-closed Capsules: Similar to gelatin capsules, these capsules come pre-sealed and do not require additional sealing.
b. Banding: A band made of HPMC or other suitable material is applied to secure the capsule halves together.
c. Heat Sealing: Heat can be used to melt and fuse the HPMC material at the joint, creating a seal.
3.Snap-fit Closure: Some hard capsules have a unique design with interlocking features on the capsule halves, allowing them to snap or lock together securely without the need for additional sealing methods.
4.Ultrasound Sealing: Ultrasonic energy can be applied to the joint of the capsule halves, generating heat and pressure to fuse them together. This method is suitable for both gelatin and vegetarian capsules.
5.Injection Molding: In some cases, hard capsules can be produced through injection molding, where the two halves of the capsule are formed and fused together during the manufacturing process.
It's important to note that the sealing or closure mechanisms may vary depending on the manufacturer, type of capsule, and specific requirements of the product or industry regulations. Manufacturers or capsule suppliers can provide guidance on the appropriate sealing method for a particular type of hard capsule.
Enteric-coated HPMC Hollow Capsules
Product introduction: It can achieve the purpose of targeted drug delivery, and is a targeted capsule product with high compatibility.
Product Category: Pharmaceutical Excipients
Product advantages: Enteric-coated hypromellose hollow capsules have the excellent characteristics of vegetable capsules and enteric-coated capsules: low water content, high stability.
