News Details

Home / News / Industry News / What is the role of empty gelatin capsules in pharmaceutical research?

What is the role of empty gelatin capsules in pharmaceutical research?

1. Drug packaging and distribution: As a packaging form of drugs, empty gelatin capsules can accommodate a variety of drug forms such as liquids, powders, and granules. For example, some drugs may be more stable because they are inside a capsule and protected from light and oxygen, extending the shelf life of the drug.
2. Controlled release of oral drugs: Empty gelatin capsules can achieve controlled release of oral drugs by changing the wall thickness, composition and structure of the capsule. For example, a certain type of long-acting capsule can gradually dissolve in the gastrointestinal tract, allowing the drug to be slowly released, maintaining stable blood drug concentration, and reducing the frequency of taking the drug.
3. Taste masking and masking: For drugs with unpleasant taste or bad taste, empty gelatin capsules can mask the bad taste by adding substances with stronger taste, or improve the taste through the coating layer of the capsule. For example, a medicine may use sweeteners or flavors to mask its bitter taste.
4. Formulation research: The flexibility of empty gelatin capsules allows researchers to adjust the formulation according to the characteristics of the drug. For example, in drug studies, researchers might try different combinations to find the most effective combination, and thus the dose that works best for patients.
5. Bioavailability studies: Researchers use empty gelatin capsules to conduct bioavailability studies to evaluate the degree of absorption of oral drugs in the body. For example, some drugs are more soluble in empty gelatin capsules, thereby increasing their absorption in the gastrointestinal tract.
6. Drug stability research: The material and manufacturing process of empty gelatin capsules have an impact on the stability of the drug. For example, some drugs may be sensitive to light, and choosing opaque capsules can effectively protect the drug from the effects of light and enhance its stability.
7. Personalized medicine: Using empty gelatin capsules, researchers can more easily prepare personalized pharmaceutical dosage forms to meet the individual differences of patients. For example, drug dosage, release rate and other parameters can be adjusted according to the patient's special needs.
8. New drug delivery system: As the basis of new drug delivery systems, empty gelatin capsules can be designed into various forms, such as nanocapsules, multi-layer capsules, etc., to improve the targeting and effect of drugs. For example, through nanoparticles wrapped in capsules, precise control and release of drugs in the body can be achieved.