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Which drugs are most suitable for enteric-coated empty capsules?

1. Antibiotics
Antibiotics play an important role in the treatment of bacterial infections, but their chemical structure is often sensitive to gastric acid and easily degraded. For example, amoxicillin is a broad-spectrum antibiotic that can effectively treat a variety of bacterial infections. Under the influence of gastric acid, the bioavailability of amoxicillin will be reduced, resulting in poor treatment effect. The use of enteric-coated empty capsules can protect the integrity of antibiotics in the stomach and release them after entering the small intestine, thereby improving the absorption efficiency of the drug. This delivery system can ensure that the drug is released at the appropriate location, maximize the efficacy, and reduce gastrointestinal discomfort.

2. Non-steroidal anti-inflammatory drugs (NSAIDs)
Non-steroidal anti-inflammatory drugs such as ibuprofen and naproxen are commonly used analgesic and anti-inflammatory drugs. This type of drug usually irritates the gastric mucosa and may lead to the risk of gastritis or peptic ulcers. To solve this problem, enteric-coated empty capsules can effectively wrap the drug in a protective coating to prevent it from being released in the stomach. This not only helps to reduce stomach discomfort, but also ensures that the drug works effectively in the small intestine, thereby better relieving pain and inflammation. This method of administration is particularly suitable for patients who need to use NSAIDs for a long time, and can significantly improve their tolerance and medication experience.

3. Certain vitamins and minerals
Vitamins and minerals are essential in maintaining good health, however, some nutrients lose their activity and reduce their bioavailability under the influence of gastric acid. For example, vitamin B12 is an important vitamin for maintaining the health of the nervous system and red blood cells, and usually needs to be absorbed through the intestines. The use of enteric-coated empty capsules can effectively avoid the interference of gastric acid and ensure that vitamin B12 is fully absorbed in the small intestine. Some minerals such as magnesium and calcium can also be better protected and released through enteric-coated capsules, thereby improving their bioavailability. This delivery system is particularly suitable for patients who need to supplement specific vitamins and minerals to ensure that nutrients can be effectively absorbed by the body.

4. Drugs for the treatment of intestinal diseases
For patients with inflammatory bowel disease (IBD) such as Crohn's disease and ulcerative colitis, treatment usually requires the use of specific drugs to reduce inflammation in the intestine. Many of these drugs will be destroyed in the environment of gastric acid, affecting their efficacy. Enteric-coated empty capsules can ensure that the drug is not degraded after passing through the stomach and is released after entering the small intestine. This method of administration can increase the local concentration of drugs in the intestine, which helps to better control inflammatory responses. At the same time, this protective packaging can also reduce gastrointestinal discomfort when patients take drugs, improve patients' medication experience, and increase compliance.